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Mast cells play a major role in neuroinflammatory conditions including neurodegenerative diseases, stroke, MS, TBI by increasing the BBB permeability and activating the brain resident immune cells microglia, and T-cells (Nakae et al., 2006
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Regarding the results of all of these studies, they found a dose-response relationship between serum homocysteine and the odds ratio of ischemic heart disease, supporting the idea that homocysteine is a causal risk factor for cardiovascular disease
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Functional MRI studies show that MB improves brain activity and memory performance
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