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They have well established adverse effects, such as respiratory depression, sedation, and constipation, which can generate or exacerbate HE, and so should be used with caution

To view or add a comment, sign in New York State health officials issued a public warning in August 2025 following a concerning rise in congenital syphilis cases outside New York City

Sitagliptin, a DPP-4 inhibitor, enhances early insulin secretion by reducing incretin and GLP-1 degradation, reduces peak glucose after oral glucose intake in overweight women with PCOS, and improves visceral obesity [169]

Does it reference "clinical studies" without linking to them

In this pilot study, 20 (1:1) participants with obesity in the GLP-1RA or control group consumed a challenge dose of alcohol, and we measured breath alcohol (BrAC) and the subjective effects of alcohol