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For broader literature on potential harms in related contexts see this review at PMC

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Needle insertion Insert the needle at a 90-degree angle to the skin surface in one smooth, swift motion The entire needle should penetrate the skinhesitation or partial insertion increases bubble risk For very thin patients or when using longer needles, a 45-degree angle may be more appropriate 4

In fact, mTG has been suggested as a new environmental factor in CD 8,9,40,41,42,43,44,45 , other ADs 22,27,45 and as even being involved in the induction of neurodegenerative diseases 7,22,39