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doi: 10.1038/s41416-019-0660-x 52 ErdelyiKDitroiTJohanssonHJCzikoraABalogNSilwal-PanditLet al
The evidence base for retatrutide remains limited compared to fully licensed medicines, given its investigational status
The Phase 3 STOP-MD3 randomized controlled trial evaluated oral SPI-1005 against a placebo over a 4-week dosing period, with secondary follow-up endpoints measured at 12 weeks
Gargs earlier trial of semaglutide also identified strong and comprehensive improvements, including weight loss, better A1C levels, and increased time in range
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