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Ensure to store this medication in a refrigerator, avoiding freezing
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Studies in mice with CNS neuron-specific GLP-1R knockout showed that liraglutide failed to induce weight loss but still improved glucose levels, suggesting that brain GLP-1Rs are necessary for the weight-lowering effect of GLP-1RAs but not essential for their glucose-lowering effects (142)
Usually taken by self-administered injection, these medications mimic the action of the natural hormone GLP-1 (glucagon-like peptide-1), which is produced in the gut and plays important roles in appetite regulation and glucose metabolism
Examples include ionizing radiation such as UV light or X-rays, and chemicals such as alkylating agents (e.g
