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4C) and partially reduced MG-induced activation of caspase-3 and cleavage of PARP (Fig

These observations suggest that obesity in KOA is not merely a background characteristic but a biologically and clinically relevant disease driver

Stay alert for new or worsening symptoms of thyroid dysfunction, such as changes in energy, mood, or bowel habits

A number of commercially available gene panels, from companies such as Blueprint Genetics, Fulgent and GHC Genetics now offer a conclusive genetic diagnosis [41,42,43]

It opened the floodgates for other pharmaceutical companies to invest in this area, since it was now a viable and FDA-recognized approach