The image below demonstrates the effects of GLP-1 agonists on various systems: The most common adverse drug reactions reported with GLP-1 agonists are as follows: These include: In New Zealand, dulaglutide (Trulicity) was the first approved GLP-1 agonist, made available for the treatment of Type 2 Diabetes in 2021
While Ozempic, Wegovy, and compounded semaglutide contain the same active ingredient, they differ in FDA approval status, dosing, intended use, and cost structure
These nutraceuticals likely act through multiple pathways as antioxidants reducing cellular stress in clock-regulating tissues, as ligands for clock-modulating receptors, and by influencing sirtuins and other clock-linked metabolic sensors (Sun et al., 2015)
The Bottom Line Who Needs a GLP-1
Improved Immune Function - Athletes with higher glutathione levels may experience fewer training interruptions due to illness, as GSH supports natural killer cell activity and proper immune response