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Directly activating GIPR in hepatocytes is an unlikely explanation for the decrease in apoC-III levels with tirzepatide [91, 92]
10.1111/apa.13992 74 MarcinkiewiczJ.CiszekM.BobekM.StrusM.HeczkoP
[12] [3] This prolonged duration of action provides some flexibility when doses are missed, but also necessitates careful timing to avoid overlapping therapeutic effects
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