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Therefore, it is not clear whether GLP-1 RA directly improves mitochondrial function, reduces ER stress, and reduces neuroinflammation, or indirectly improves these mechanisms by lowering blood glucose and improving IR
They are the standard of care for safe, sustainable weight loss on these medications
Blood in stool
Some people develop bile acid diarrhoea after gallbladder removal, which may require assessment and possibly treatment with bile acid sequestrants if symptoms are troublesome
Therefore, in clinical practice, close monitoring of blood glucose levels is recommended for individuals with diabetes, particularly those receiving combination antidiabetic therapy or during the early phase of dose adjustment
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