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[1] [2] It belongs to a class of drugs called glucagon-like peptide-1 (GLP-1) receptor agonists , which work by mimicking the action of a naturally occurring hormone in the human body called GLP-1

Oral GLP-1s dosing Oral GLP-1s are available in different dosage strengths

Upregulation of MITF enhances expression of tyrosinase, a key enzyme in the melanin synthesis pathway

In 2024, the FDA approved resmetirom (Rezdiffra) for adults with noncirrhotic NASH with F2F3 fibrosis, marking the first approved pharmacotherapy specifically for this condition

It may do this by reducing sodium (salt) and fluid retention, improving energy use by the heart, reducing inflammation and preventing or reversing cardiac enlargement