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It has a molecular weight of approximately 1419.53 Da and carries a net negative charge at physiological pH
For example, HSP90 inhibitors such as ganetespib not only disrupt chaperone function but also enhance autophagy, leading to the degradation of oncogenic proteins in cancer
An empty stomach reduces enzymatic breakdown and may improve peptide transport across the gut lining
1.2 10 5 SHSY-5Y cells were subjected to similar treatment as above except 1 mM MPP + (for 24 h) was used to induce ROS
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