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The honest boundary is that even the coherent pairing is a mechanistic hypothesis with no human validation, so the most defensible research posture is to study the single compound at its documented dose first, and treat any combination as a further, clearly-labelled research question rather than a default
[2] [4] If you are of childbearing potential, you must use effective contraception during methotrexate treatment and for at least 3 months after stopping
A 2023 study showed that those who consumed 0.66g of protein per Kg per day had low levels of Glutathione vs those who consumed 1.0g of protein per Kg per day
Youll make any necessary adjustments and check in with your provider, and also check in with a registered dietitian regularly to make sure youre getting the most out of your treatment
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