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Citation 47 ) insulin-like growth factor-I receptor,Citation 47 ) platelet-derived growth factor receptor,Citation 48 ) vascular endothelial growth factor receptor,Citation 49 ) and nerve growth factor (NGF) receptor,Citation 50 ) implicating the modulation of multiple growth factor-activated signaling pathways

In fact, more than 25% of diagnosed patients have an autoantibody (auto-Ab)-driven autoimmune disease [4, 5]

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