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As noted above, 5-cholesten-3-one is not showing any activity with the mammalian enzymes, presumably due to steric hindrance by the bulky sidechain (Figure 8)
Nat Commun 11 , 4071 (2020)
This guide has summarized the findings of published studies and highlighted areas where further research may be warranted
The cAMP signalling pathway activates CREB through PKA, p38 and MSK1 in NIH 3T3 cells
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