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Ibuprofen is insoluble in water, thus organic solvents such as ethanol, DMSO or dimethyl-formamide are needed for its pharmaceutic formulations that makes its safe applicability a challenge [70]
We constructed standardized experimental models encompassing murine full-thickness burn injuries [13], rat dermal incisional wounds [13], and rodent skeletal muscle contusion models (Figure S1)
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doi:10.3390/ijms26062691 Gatta M, Dovizio M, Milillo C, et al
Review on antioxidant and skin tone improvement 4
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