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Amyotrophic lateral sclerosis Amyotrophic lateral sclerosis (ALS) is a fatal progressive neurological disorder characterized by muscle paralysis caused by the degeneration of motor neurons in the brain, brainstem and spinal cord
injections of 100 nmol kg 1 MK-801 ( n = 9 mice and 4 cages), 100 nmol kg 1 GLP-1 ( n = 10 mice and 4 cages), 100 nmol kg 1 GLP-1MK-801 ( n = 10 mice and 4 cages), or vehicle (isotonic saline, n = 10 mice and 4 cages) for 14 days
Advanced dosing strategies Beyond the standard titration protocol, experienced researchers sometimes employ more nuanced dosing approaches based on their individual response patterns
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