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Morris, M
A study exploring the response of Atgstu19 and Atgstu24 mutants to TuMV infection showed significant differences in specific AtGSTU gene expression, virus concentration, ultrastructural alterations, glutathione content, and glutathione transferase and reductase activities compared with Col-0 (wild-type) and mock-inoculated plants ( Atgstu24 mutants had a resistance-like reaction to TuMV (with a high decrease in virus gene expression and movement) compared to susceptible Col-0 plants, suggesting that GSTU24 may suppress plant resistance
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These in vitro observations not only provide an initial basis for in vivo treatment regimens focusing on the stimulation of endogenous hepatic glutathione levels, but could also contribute to an optimization of treatment intervals to limit the risk of adverse effects when NFT is administered as an antibiotic
The responsible first step in either case is testing, not guessing
