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The guidelines warn, however, that GLP-1 receptor agonist therapy is not indicated for all patients and should be used with caution in patients with a history of significant gastrointestinal disease, such as a diagnosis of gastroparesis, due to a possible exacerbation of the condition with incretin mimetic therapy
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Oral Wegovy Clinical Trial Results (OASIS 4) Data published in the New England Journal of Medicine show that oral semaglutide 25 mg taken once daily resulted in an average weight loss of 16.6 percent among participants who followed the dosing protocol
