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Studies show that when people stop taking them, a significant portion of the weight typically returns within 12 months

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DOI: 10.1016/j.pharmthera.2017.06.012 [Google Scholar] Wu AY, Peebles RS

The SURPASS clinical trial programme has provided evidence of these metabolic improvements, though it's important to note that long-term cardiovascular outcome studies are ongoing, and Mounjaro does not currently have a UK-licensed indication for cardiovascular risk reduction