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An earlier 12-week trial in 300 obese adults produced a genuine positive signal the 1 mg daily dosing arm showed a statistically significant 2.8 kg mean weight loss versus 0.8 kg in the placebo group and that result is what justified moving into the larger Phase IIb trial

This is a strong study design though with only 6 participants, the statistical power is very limited

Adults over 50, vegetarians and vegans, and people with gastrointestinal issues may need to take vitamin B12 supplements to avoid deficiency

The only way to address high B12 is to identify and treat the underlying cause or to stop the exogenous source

So, with that in mind, is it really the Wunderkind everyones claiming it to be