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Alternative medicine review, 11(4)
Gotoh T, Hattori S, Nakamura S, Kitayama H, Noda M, Takai Y, Kaibuchi K, Matsui H, Hatase O, Takahashi H, Kurata T
At 48 weeks, there was progressive decrease in weight (secondary outcome) ranging from 8.7% to 24.2% with retatrutide versus 2.1% with placebo [3]
Injection pain is the brief discomfort felt during needle insertion (usually minimal with semaglutide), while post-injection reactions like redness or swelling develop afterward and are unrelated to injection technique
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