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Its worth noting that Tirzepatide (via Mounjaro) is available by prescription in Canada with a type 2 diabetes diagnosis, and Semaglutide (Wegovy) is available for weight management

However, genetic testing for vitamin D-related polymorphisms is not yet routinely available or standardized for clinical use

In terms of duration of action, exenatide and lixisenatide are considered short-acting GLP-1 receptor agonists with a half-life of approximately 25 h, while dulaglutide, liraglutide and exenatide-LAR are considered long-acting GLP-1 receptor agonists with a half-life of 12 hseveral days

Research endpoints include epithelial-barrier integrity, cytoprotective signaling, inflammatory-response markers, peptide biodistribution, and comparisons with parenteral delivery models

However, due to a shortage of Wegovy, healthcare providers began prescribing Ozempic to those seeking weight loss