The depletion of GSH results in elevated levels of oxidative stress, molecular impairment, and consequent cell ferroptosis (46)
28 Additionally, a 16-week trial of supplementation with GlyNAC (which boosts glutathione levels) in older adults improvedand in some cases reversedmultiple hallmarks of aging, including inflammation, mitochondrial dysfunction, and oxidative stress
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Zhan GY et al
Arsova B, Hoja U, Wimmelbacher M, Greiner E, stn , Melzer M, Petersen K, Lein W, Bornke F (2010) Plastidial thioredoxin z interacts with two fructokinase-like proteins in a thiol-dependent manner: evidence for an essential role in chloroplast development in Arabidopsis and Nicotiana benthamiana