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Common symptoms can include: Extreme fatigue Lethargy Loss of appetite headaches Feeling faint or dizzy Breathlessness Headaches Heart palpitations Tinnitus Additional symptoms of B12 deficiency can include psychological problems such as low mood, irritability, depression, cognitive changes, or blurred memory

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In the initial larger, higher resolution, dataset of Cagri-CTR-Gs ( N = 1), density was observed for the proximal region of the conjugated lipid at the peptide N-terminus that was consistent regardless of peptide conformation (bypass or CT-like) and supports modelling the Glu linker and a short segment of acyl chain in a different orientation to that observed in the AMY 1 R complex (Figs