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Because of how vitamin B12 is absorbed, the most common risk factors for B12 deficiency are: Genetic susceptibility : Some people genetically produce less intrinsic factor and stomach acid needed for B12 absorption
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Intramuscular (IM): Less common but sometimes used for deep tissue or joint injuries
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thus, more studies are needed to establish optimal dosing regimens and identify which combination approaches provide the most meaningful dermal benefits, especially in aging women
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