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4), the formation of a CoPP:GSH complex is expected to introduce hydrophilic functionalities to CoPP
It has been used extensively in animal studies, human cell models, and increasingly in off-label therapeutic settings, with minimal toxicity or organ stress reported
Long-term evidence beyond 24 weeks is limited
High levels of reactive oxygen species (ROS) in cells can directly affect DNA biological processes, leading to DNA damage
Pros: Potential for enhanced biological activity
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