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While the RNI for maintenance is only 1.5 g daily, therapeutic oral doses typically range from: 50-150 g daily for mild deficiency prevention in at-risk groups 1,000-2,000 g daily for treating confirmed deficiency without malabsorption Some formulations contain up to 5,000 g, though there is no proven additional benefit over 1,000-2,000 g for most patients The reason for this dosage discrepancy lies in absorption efficiency
Additionally, choline plays a role in keeping our brains healthy
The split dosing approach maintains more consistent NNMT inhibition throughout the day, potentially enhancing metabolic benefits
Other treatment options have traditionally included surgical removal (excision), liquid nitrogen (freezing it off), curettage (scraping it off, often with electrical controlled burning), and lasering it off
