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While the rigorous study confirmed that high-dose CoQ10 was entirely safe and well-tolerated, it did not demonstrate a statistically significant reduction in overall symptom severity compared to the placebo over the 6-week intervention periods
Based on these results, Authors suggested that oral ingestion of LC, combined with CHO for activation carnitine transport into the muscles, should take ~ 100 days to increase muscle carnitine content by ~ 10% [26]
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In one study, people regained two-thirds of the weight they had lost within a year of stopping treatment
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