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Second, we correlated peripheral GSH levels with clinical symptoms and neurocognitive functions

Consistent with this finding, thrombin or vehicle control was added for 10 min, after which platelet lysates were prepared, and assessed by Westernblot analysis

GIP (glucose-dependent insulinotropic polypeptide) receptor activation primarily enhances insulin secretion, improves fat tissue metabolism, and may contribute to central appetite suppression

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In SURMOUNT-2, the mean WL was up to 15.7% with tirzepatide 15 mg compared to 3.3% WL with placebo at 72 weeks for people with obesity and T2D [47]