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The pattern typically unfolds over months: tirzepatide produces weight loss and inflammation reduction, which allows a gradual steroid taper, which further improves weight and metabolic health, which may allow additional steroid reduction
Many find the morning convenient as the stomach is naturally empty after sleeping
Since tirzepatide may slow gastric emptying as part of its mechanism of action, patients with pre-existing severe gastroparesis could experience worsening of symptoms, including nausea, vomiting, and potential complications related to delayed gastric emptying
Current Gerontology and Geriatrics Research, 2012 , 302875
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