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Wang B, Feng L, Jiang WD, Wu P, Kuang SY, Jiang J, et al

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These effects result from semaglutide's action on GLP-1 receptors throughout the digestive tract and typically improve after 4-8 weeks at a stable dose

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The investigators conducted a multicenter, double-blind, placebo-controlled, active-controlled phase 3a trial (ClinicalTrials.gov ID: NCT05567796) evaluating the efficacy and safety of the combination of semaglutide and cagrilintide in adults without diabetes with a body-mass index (BMI) of greater than or equal to 30 or greater than or equal to 27 with at least one obesity-related complication

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