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Glucagon-like peptide-1 receptor agonists activate rodent thyroid C-cells causing calcitonin release and C-cell proliferation
PT-141 is a cyclic heptapeptide with a lactam bridge that restricts conformational flexibility, preventing the peptide from adopting the shape required for high-affinity MC1R binding
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In mouse models of cecal ligation and puncture (CLP)-induced sepsis, plasma-derived EVs affected RBC deformability, increasing RBC rigidity [387]
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