Precursors of GSH or GPX biosynthesis, various small molecule activators related to the GSH system and some novel therapeutic approaches, such as exosomes and gene therapy, can boost the activity of the GSH system and reduce cardiac damage and ferroptosis
Dr Harish is a Celebrity Aesthetic Physician and Surgeon, having worked with numerous South Indian film personalities while maintaining a patient-first approach that blends artistry with medical precision
Lephart have no conflicts of interest to declare
In addition, supplementing the raw materials (cysteine, glycine, glutamate, and selenium) for synthesizing GSH or GPX to achieve an elevated GSH system in the myocardium is another feasible strategy
It often coexists with POTS and shares mechanisms like mitochondrial dysfunction, systemic inflammation, and oxidative stress