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The patent gives exceedingly little information about the isolation process, stating only that a variety of relatively crude chromatographic approaches were utilized (i.e., ion-exchange and gel) followed by dialysis (i.e

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10,14,15,16 Furthermore, paracetamol exposure in the developing lung is associated with increased expression of antioxidant response genes, pro-inflammatory cytokines (e.g., IL-6), and a metabolic shift toward increased mitochondrial workload

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