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Embodiment 3 [0052] Example 3: R 1 -His(R 2 Synthesis of )-Aib-OH [0053] [0054] R 1 =Fmoc, R 3 =Trt or Mmt or Mtt, R 2 =H [0055] At room temperature, weigh 62.66g of intermediate I crude product and add it to 250ml of dichloromethane, stir and dissolve, measure 188ml of trifluoroacetic acid and add it to the reaction flask, add 25.90g of triisopropylsilane, stir at room temperature for 4 hours, and the raw materials react

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If the research protocol can tolerate this level of uncertainty, use the peptide in non-critical pilot work rather than in formal study cohorts

Vitamin C is an essential nutrient with established dietary recommendations during pregnancy and is commonly included in prenatal nutrition plans when consumed within recommended limits

Spiering BA, Kraemer WJ, Vingren JL, Hatfield DL, Fragal MS, Ho JY, Maresh CM, Anderson JM, Volek JS