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One study found that use of the pramlintide/metreleptin combination resulted in 11.5 kg weight loss over 20 weeks compared with 7.4 kg and 7.9 kg weight loss respectively in participants receiving either metreleptin or pramlintide monotherapy [88]

Consult your healthcare provider before use if you are pregnant, breastfeeding, or scheduled for surgery

Once you reach your therapeutic dose, the expected rate of weight loss is 0.5-1% of your body weight per week

In people with hemochromatosis, excess iron in the sweat glands can cause a bronze skin tone and dark spots

The peptide spreads throughout the body, so precise injection location matters less than with BPC-157