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Compared to placebo, it has been shown to significantly lower HbA1c by up to 2.07% when administered as a once-weekly subcutaneous injection at a maximum dose of 15 mg

The biologic effects of IGFs signaling on cancer Once activated by the ligands, IGF-IR and InsR may initiate diverse signaling pathways to regulate cell proliferation, differentiation, survival, metabolism, migration, and stemness (Fig

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