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It highlights thiamines (B1) role in catalyzing enzymes such as Pyruvate Dehydrogenase and -Ketoglutarate Dehydrogenase, (e) riboflavins (B2) contribution to fumarate production, and niacins (B3) importance in the synthesis of -Ketoglutarate and succinate (30, 31, 3335)

alternative contraception is recommended for 4 weeks after starting or increasing doses

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Community sources describe the abdomen as offering the most consistent absorption