Retatrutide is an investigational triple receptor agonist targeting GLP-1, GIP, and glucagon receptors, not yet licensed by the MHRA or EMA, and currently in Phase 2 and Phase 3 clinical trials
In studies, after 52 weeks, participants on the highest dose of Mounjaro (15 mg per week): Lowered their total cholesterol by about 5.6 percent Lowered their triglycerides by 22.5 percent Lowered their LDL (bad) cholesterol by 7.9 percent Lowered their VLDL cholesterol by 21.8 percent Increased their HDL (good) cholesterol by 10.8 percent Additionally, a meta-analysis (analysis of data from several clinical trials) from The Lancet found that Ozempic lowered cardiovascular risk and even decreased the risk of death in people with diabetes and heart disease
Other potential side effects include headaches and digestive discomfort
However, this is not always the case
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