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Poor storage means degraded peptide, and degraded peptide means compromised data
When NNMT runs too high in fat tissue, it wastes a form of vitamin B3 that the body needs to make NAD+
The goal is not to stay at sub-therapeutic doses forever but to build tolerance slowly enough that your body can adapt without the nausea, vomiting, and bloating that characterize rapid titration
Gallstones and gallbladder symptoms typically do not resolve on their own
It is especially important for high-energy organs like the heart and muscles
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