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It is also worth noting that APAP is used in combination with other drugs, particularly opioids and diphenhydramine, without public awareness (Rajaram and Subramanian, 2018)

Mass spectrometry analysis confirmed co-purification of endogenous members of the Ube2e E2 conjugating enzymes family, including Ube2e1, Ube2e2, Ube2e3 and Ube2d3 in the complex (Supplementary Fig

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