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First, glutamate-cysteine ligase (GCL) catalyzes the conjugation of cysteine and glutamate, which results in the formation of \(\gamma\)-glutamylcysteine

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The hormone has far greater timeframe to circulate around the body, bind to receptors, and exert its effects

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doi: 10.1046/j.1365-2710.2003.00493.x 49 NdlovE.VrbovM.CeslaP.JankoviovB.VenturaK.RouarT