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These drugs offer dual benefits, improving glycemic control while boosting weight loss, which makes them a preferred option in managing both type 2 diabetes and obesity

This hypothetical mechanism with deeper desensitization of KARs compared to AMPARs is consistent with slower recovery from desensitization observed in KARs compared to AMPARs (Gangwar et al., 2024b

The activation of the PI3K/Akt signaling pathway by IGF-1 is the possible mechanism through which it promotes muscle building

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