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Research using high-glucose-injured human retinal pigment epithelial cells (ARPE-19) showed Epithalon treatment restored impaired wound healing, reduced intracellular reactive oxygen species accumulation, and increased antioxidant gene expression

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None of these pathways have been confirmed in a dedicated human sexual-function trial, but the upstream science is grounded in peer-reviewed literature

doi:10.3390/biology10060456 Zawieja E, Durkalec-Michalski K, Sadowski M, Glowka N, Chmurzynska A

The damage can range from a non-detectable injury over limited traumatic annular tears or nucleus pulposus prolapse to a complete destruction of the disc organ such as in fracture dislocations