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The clinical rationale is straightforward: deliver the 5-alpha reductase inhibitor directly to the scalp to reduce local DHT while minimizing systemic absorption and its associated side effects
J Appl Microbiol 116:304313
And I think some animal studies by that same group have shown that
Jorns, MS (22 July 2014)
In addition, these patients also showed signs of immune and endothelial dysfunction, elevated oxidative stress, inflammation, and impaired mitochondrial function
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