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doi: 10.1038/s41574-018-0048-7 58 BatumKCinarNSahinSCakmakMAKarsidagS
Age-dependent oxidative stress elevates arginase 1 and uncoupled nitric oxide synthesis in skeletal muscle of aged mice
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After matching, average age at index prescription for non-diabetic, obese men was 37.8 7.8 and average BMI at index prescription was 38.6 5.6
Ozempic's once-weekly injection schedule, its demonstrated 1.5-1.8% HbA1c reduction, and the SUSTAIN cardiovascular outcomes trial data showing 26% reduction in major cardiovascular events in T2DM patients with established cardiovascular disease collectively built a clinical case that endocrinologists and cardiologists find compelling for guideline-aligned prescribing
