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Carnitine octanoyltransferase (CrOT) is predominantly found in peroxisomes and plays a key role in the transfer of medium-chain acyl groups from the peroxisomes to the cytoplasm and mitochondria for further degradation [27]

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While tirzepatide reduces appetite and calorie intake, L-carnitine theoretically optimizes fat oxidation during the calorie deficit that results

However, both ingredients need meaningful doses

Chlorogenic acid inhibits trimethylamine-N-oxide formation and remodels intestinal microbiota to alleviate liver dysfunction in high L-carnitine feeding mice