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1 Introduction Metabolic dysfunction-associated steatotic liver disease (MASLD), formerly known as non-alcoholic fatty liver disease (NAFLD), is a growing epidemic associated with metabolic disease ( Glucagon-like peptide-1 receptor agonists (GLP-1 RAs), including liraglutide, exenatide, semaglutide, beinaglutide, and dulaglutide, are commonly used in clinical practice to manage blood sugar and body weight

The ADA guidelines emphasize individualized treatment approaches that balance glycemic control with cardiovascular risk reduction, which may include careful use of multiple medications affecting different metabolic pathways

The acylation at position 26 is the pharmacokinetic change

There is some anecdotal evidence

Protein provides satiety, preserves lean muscle mass during continued caloric deficit, and supports metabolic rate