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Published online April 2026:101314

Severe GI adverse reactions were reported in 4.1% and 0.9% of Wegovy -injection treated and placebo treated patients, respectively, and in 2% of Wegovy tablet-treated and 0% of placebo treated patients, respectively

E.AnderssonA.et al (2011)

160 After multiple oral doses of 14 mg oral semaglutide, the T max of levothyroxine was delayed by 2 h, with a 12% decrease in the C max and a 33% increase in the AUC, indicating potential clinical relevance (Table 5)

These discrepant results call for further translational and mechanistic studies that would explore the direct effects of this medication on placental function, Grechukhina said