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Kumar refers to GLP-1 prescriptions as one of the greatest medical breakthroughs of the decade. They have sparked a social phenomenon, too

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The vast majority of myelofibrosis patients eventually develop anemia, causing them to discontinue treatments and require transfusions, said Nina Mojas, senior vice president of oncology global product strategy at GSK in the same press release

The FDA approved GLP-1s after testing them in large clinical trials (such as STEP and SURMOUNT ) at specific doses and intervals

The result "makes perfect biological sense," says Adam Auton, study co-author and vice president of human genetics at the 23andMe Research Institute